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Knee Replacement Surgery, Knee Surgery, Total Knee Arthroplasty

Knee Replacement Surgery

Major orthopaedic surgery involving the lower extremity — hip or knee replacement surgery or hip fracture surgery — is associated with a high risk of venous thromboembolic disease (VTE).

VTE is the most frequent serious complication following knee replacement surgery. It is the most common cause for rehospitalisation in this patient group.119, 376

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Knee Surgery

Studies of the natural history of deep vein thrombosis (DVT) after orthopaedic surgery have shown that, in many patients, venous thrombosis causes no symptoms. Because of ongoing venous stasis during the recovery period, some thrombi expand. These thrombi may break free to cause pulmonary embolism (PE), often after the patient leaves the hospital.119 Current recommendations regarding the duration of anticoagulation following hip and knee surgery are based on this understanding of the chronology of VTE.119

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Total Knee Arthroplasty

The duration of anticoagulation needed to prevent DVT after hospital discharge is an important aspect of care. Current guidelines recommend extending prophylaxis for 10 days after knee arthroplasty and for four to six weeks after hip arthroplasty and hip fracture surgery. Extending prophylaxis for four weeks is also recommended for patients after abdominal cancer surgery.119, 334, 284 However, in practice, many patients may not receive this duration of treatment.377

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Find out more about knee replacement surgery, knee surgery, and total knee arthroplasty.

See also: Embolism Pulmonary Sign

See also: Apixaban

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