Pulmonary embolism (PE) occurs when a part of a thrombus, usually dislodged from a deep vein thrombosis (DVT), passes into the pulmonary circulation, occluding the pulmonary arteries. PE is a potentially life-threatening condition and is the most common reason for preventable hospital death. Rapid diagnosis is crucial, but a diagnosis of PE can often be missed because of its non-specific clinical symptoms. Long-term complications of PE include chronic thromboembolic pulmonary hypertension (CTEPH). The Wells’ score is one scoring system that is commonly used to predict the clinical probability of PE. Computed tomography (CT) pulmonary angiography has become the method of choice for diagnostic imaging in patients with suspected PE, although other diagnostic methods are now available. The 2014 update of the European Society of Cardiology (ESC) guidelines for the management of PE brings about new recommendations for prognosis and treatment.