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Thrombosis News

• Older women with AF face higher stroke risk than men Older women with AF face higher stroke risk than men In a study that examined use of the anticoagulant medication warfarin and risk of stroke in older patients following a diagnosis of atrial fibrillation, women, especially those ages 75 and older, had a higher risk of stroke than men, regardless of their risk profile and use of warfarin.
• Venous thromboembolism: EINSTEIN transforms anticoagulant therapy in acute PE A report by the EINSTEIN-PE investigators, which was presented at the ACC Scientific Sessions in March 2012 and published simultaneously in the New England Journal of Medicine, represents a potential tectonic shift in the care of patients with acute pulmonary embolism (PE). The study gives solid evidence for the efficacy and safety of rivaroxaban, which is an oral alternative to subcutaneous injection of heparins followed by oral administration of coumarins such as warfarin.
• Aspirin and Warfarin Equally Effective for Most Heart Failure Patients, Study Suggests Neither aspirin nor warfarin is superior for preventing a combined risk of death, stroke, and cerebral hemorrhage in heart failure patients with normal heart rhythm, according to a landmark clinical trial published in the May 3, 2012, New England Journal of Medicine.
• Warfarin May Be OK for Heart Device Implantation Continuing oral anticoagulation when undergoing implantation of a cardiac device appears to minimize the bleeding risk compared with a heparin bridging strategy, a meta-analysis showed.