Symptom of Thrombosis, Thrombosis, Venous Thromboembolism
Symptom of Thrombosis
Clinical symptoms of deep vein thrombosis include swelling, pain, and discolouration of the affected extremity. Physical examination may reveal calf tenderness, unilateral oedema, warmth, skin discolouration, and superficial venous dilation.25, 43 However, many of these signs and symptoms can occur in other conditions and therefore have a low predictive value for diagnosing DVT.42
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Thrombosis
The pathological formation of a blood clot, or thrombosis, poses significant health risks. Thrombosis plays a role in heart attack, ischaemic stroke, cardioembolic stroke in patients with atrial fibrillation (AF), and venous thromboembolic disease (VTE).5, 8, 18
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Venous Thromboembolism
Venous thromboembolism (VTE) is a well-recognised cause of preventable morbidity and mortality in hospitalised patients. About one in four cases of VTE is associated with hospitalisation, and VTE may occur in patients hospitalised to treat medical illness as well in those undergoing surgery.3, 64
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See also: Knee Replacement
See also: Hip Fracture
- 25 - Turpie AG, Chin BS, Lip GY. Venous thromboembolism: pathophysiology, clinical features, and prevention. BMJ. 2002;325(7369):887-890.
- 43 - Kearon C, Hirsh J. Cardiovascular medicine: XVIII. Venous thromboembolism. In: Dale DC, ed. ACP Medicine. New York, NY: WebMD, Inc; 2007:1-15. http://www.acpmedicine.com/acp_home.htm. Accessed February 12, 2008.
- 42 - Ramzi DW, Leeper KV. DVT and pulmonary embolism: Part I. Diagnosis. Am Fam Physician. 2004;69(12):2829-2836.
- 5 - Fuster V, Moreno PR, Fayad ZA, Corti R, Badimon JJ. Atherothrombosis and high-risk plaque: part I: evolving concepts. J Am Coll Cardiol. 2005;46(6):937-954.
- 8 - Tapson VF. Acute pulmonary embolism. N Engl J Med. 2008;358(10):1037-1052.
- 18 - Waldo AL. Anticoagulation: stroke prevention in patients with atrial fibrillation. Med Clin North Am. 2008;92(1):143-159, xi.
- 3 - 1. Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6)(suppl):381S-453S.
- 64 - Francis CW. Clinical practice. Prophylaxis for thromboembolism in hospitalized medical patients. N Engl J Med. 2007;356(14):1438-1444.
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